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· TRAF6 and Skp2-SCF are identified as two E3 ubiquitin ligases mediating K63-linked ubiquitination and activation of Akt in response to growth factor insulin-like growth factor-1 (IGF-1) and...
K63-linked polyubiquitin chains exert nonproteolytic functions in vivo, such as protein trafficking, kinase/phosphatase activation, and DNA damage control, all of which might be important in regulation of cancer survival …
· : TRAF6Lys63(K63-Ub)""TAK1。,TRAF6 E3IL-1K63-Ub、TAK1、IL-8。 E3TRAF6,Pellino1Pellino2K63-Ub。 IL-1K63-Ub …
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· ,K63。 Hirokazu Arimoto,S-guanylationK63,S-guanylation。 MetAP2、FKBP12、BET、TSPOAUTAC …
· The K63-linked ubiquitination of p62 at Lys7 prevents its self-oligomerization and targeting to the autophagosome. Taken together, our study suggests that the ISGylation of TRIM21 plays a vital...
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Mill is built using Mill. To begin, first download & install Mill as described in the documentation above. As Mill is under active development, stable releases may not be able to build the current development branch of Mill. It is recommended to install the latest unstable release manually. IntelliJ Setup